Dorien Bangma

FDM IN NEURODEGENERATIVE DISEASES | 87 Study Country Design Sample characteristics FDM task (scale) Main outcome Conclusion Gerstenecker, Hoagey et al. (2017) + USA CS MCI (n=31) / Type: amnestic FCI (scores on domains 1-7, total score based on domains 1-7) - Patients with MCI showed significantly lower FDM performances than HC on the FCI total score and on all domains separately, with the exception of ‘basic money skills’ and ‘identifying fraud/financial judgment’. MCI (amnestic) ≤ HC - age (y) 71.9±7.1 - education (y) 15.2±2.5 - 69.7% male - MMSE 26.9±2.1 * - DRS 130.7±4.9 * HC (n=60) - age (y) 70.6±7.0 - education (y) 16.0±2.3 - 72.1% male - MMSE 29.1±1.2 - DRS 138.9±2.8 Gerstenecker et al. (2018) + USA CS MCI (n=149) / Type: amnestic FCI (scores on 4 domains extracted from factor analyses) - Patients with MCI showed significantly lower FDM performances than HC on all domains, with the exception of one which was described as ‘financial conceptual knowledge’. MCI (amnestic) ≤ HC - age (y) n.r. - education (y) n.r. - % male n.r. - n.r. HC (n=179) - age (y) n.r. - education (y) n.r. - % male n.r. - n.r. Gerstenecker et al. (2019) + USA CS MCI (n=65) / Type: amnestic FCI (scores on domains 1-7, 9, total score based on domains 1-7, 9) - Patients with MCI showed significantly lower FDM performances than HC on the FCI total score and on all domains separately, with the exception of ‘basic money skills’ and ‘identifying fraud/financial judgment’. MCI (amnestic) ≤ HC - age (y) 72.6±7.4 - education (y) 15.2±2.6 - 49.2% male - MMSE 27.4±3.2 * HC (n=64) - age (y) 70.6±7.4 - education (y) 15.8±2.3 - 29.7% male - MMSE 28.7±3.9 Giannouli & Tsolaki (2014) + Greece CS MCI (n=46) / Type: amnestic FDM test b (scores on six domains) - Patients with MCI showed significantly lower FDM performances than HC on all domains of the FDM test. MCI (amnestic) < HC - age (y) 69.7±9.0 ? - education (y) 9.4±4.3 ? - % male n.r. - MMSE 26.9±1.9 ? HC (n=83) - age (y) 73.6±9.8 - education (y) 8.1±4.6 - % male n.r. - MMSE 29.5±1.2 Giannouli et al. (2018) + Greece CS MCI (n = 20) / Type: amnestic LCPLTAS (scores on seven domains, total score based on all domains) - Patients with MCI showed a significantly lower FDM performance than HC on the LCPLTAS total score and on all domains separately. MCI (amnestic) < HC - age (y) n.r. c - education (y) n.r. c - % male n.r. c - MMSE 27.0±2.9 ? - HC (n = 22) - age (y) n.r. c - education (y) n.r. c - % male n.r. c - MMSE 29.2±0.9 Table continues on the next page