Stefan Elbers

18 Chapter 1 patients with chronic pain. The results include an overview of the variability in dose and content between the programmes. The study adopts a GRADE approach towards determining the effectiveness of generic self-management interventions on outcomes related to daily life functioning and quality of life. To further accommodate the paucity of information on the prevention of relapse, we opted for a co-design approach. This method is characterized by increments in knowledge over multiple development cycles, and by the continuous involvement of stakeholders in the design process. In Chapter five , we reflect on the value and function of the co-design approach by presenting the intervention development project as a case study and by systematically reflecting on each design phase. Chapter six contains the first field test of the prototype that originated from this project. Based on these findings, we further developed the prototype into an mHealth application. In Chapter seven , we outline this process and present a study protocol for a randomized controlled trial to test its effectiveness. Chapter eight contains the general discussion. In this section, we will specifically evaluate the implications for both clinical practice and research and discuss the potential impact of our main outcomes . Box 1 includes all the questions that we address in this thesis.