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102 Chapter 4 Drago, L., Bortolin, M., Taschieri, S., De Vecchi, E., Agrappi, S., Del Fabbro, M., Francetti, L. & Mattina. R. (2017). Erythritol/Chlorhexidine Combination Reduces Microbial Biofilm and Prevents its Formation on Titanium Surfaces in Vitro. Journal of Oral Pathology & Medicine, 46, 625-631. doi:10.1111/jop.12536. Drago, L., Del Fabbro, M., Bortolin, M., Vassena, C., De Vecchi, E. & Taschieri. S. (2014). Biofilm Removal and Antimicrobial Activity of Two Different Air-polishing Powders: An in Vitro Study. Journal of Periodontology, 85, e363-e369. doi:10.1902/jop.2014.140134 Dena, H., Cionca, N., Combescure, C. & Mombelli, A. (2018). The Diagnosis of Peri-Implantitis: A Systematic Review on the Predictive Value of Bleeding on Probing. Clinical Oral Implants Research, 29, 276-293. doi:10.1111/clr.13127. Esposito, M., Grusovin, M. G. & Worthington, H. V. (2012). Treatment of Peri-Implantitis: What Interventions are Effective? A Cochrane Systematic Review. European Journal of Oral Implantology, 5, S21-S41. doi:25726. Garaicoa-Pazmino, C., Sinjab, K., & Wang, H-L. (2019). Current Protocols for the Treatment of Peri- Implantitis. Current Oral Health Reports, 6, 209-217. doi:10.1007/s40496-019-00227-4. Hägi, T.T., Hofmänner, P., Salvi, G.E., Ramseier, C.A. & Sculean, A. (2013) Clinical outcomes following subgingival application of a novel erythritol powder by means of air-polishing in supportive periodontal therapy: a randomized, controlled clinical study. Quintessence International, 44, 753–761. doi: 10.3290/j.qi.a30606. Hallström, H., Persson, G. R., Lindgren, S. & Renvert, S. (2017). “Open Flap Debridement of Peri- Implantitis with Or without Adjunctive Systemic Antibiotics: A Randomized Clinical Trial. Journal of Clinical Periodontology, 44, 1285-1293. doi:10.1111/jcpe.12805. Hashino, E., Kuboniwa, M., Alghamdi, S.A., Yamaguchi, M., Yamamoto, R., Cho, H. & Amano, A. (2013). Erythritol alters microstructure and metabolomic profiles of biofilm composed of Streptococcus gordonii and Porphyromonas gingivalis. Molecular Oral Microbiology, 28, 435- 451. doi: 10.1111/omi.12037. Hentenaar, D. F. M., De Waal, Y. C. M., Strooker, H., Meijer, H. J. A., Van Winkelhoff, A. J. & Raghoebar, G. M. (2017). Implant Decontamination with Phosphoric Acid during Surgical Peri-Implantitis Treatment: a RCT. International Journal of Implant Dentistry, 3, 33-35. doi:10.1186/s40729-017- 0091-5. Hentenaar, D., De Waal, Y., Stewart, R. E., Van Winkelhoff, A. J., Meijer, H., & Raghoebar, G. M. (2021). Erythritol air-polishing in the non-surgical treatment of peri-implantitis: A randomized controlled trial. Clinical Oral Implants Research, 32, 840–852. doi.org/10.1111/clr.13757 Jentsch, H.F.R., Flechsig, C., Kette, B. & Eick, S. (2020). Adjunctive air-polishing with erythritol in nonsurgical periodontal therapy: a randomized clinical trial. BMC Oral Health, 20, 364. doi: 10.1186/s12903-020-01363-5.