Diederik Hentenaar

45 Biomarkers in crevicular peri-implant fluid At last, for future research groups with interest in sRANKL and INF-γ, recoverability experiments seem recommended when using a ThermoFisher Luminex assay plate, in order to obtain accurate and reliable outcomes. CONCLUSION PICF diagnostics of implants diagnosed with peri-implantitis showed higher levels of IL-1β and MMP-8 compared to healthy implants. Non-surgical therapy did not seem to influence the inflammatory immune response. Hence, evaluation of non-surgical peri- implantitis therapy outcome using PICF diagnostics does not seem helpful. 2