Diederik Hentenaar

CONTENTS Chapter 1 General introduction 7 Chapter 2 Biomarker levels in peri-implant crevicular fluid of healthy implants, untreated and non-surgically treated implants with peri-implantitis 29 Chapter 3 Erythritol air-polishing in the non-surgical treatment of peri-implantitis; a 1-year randomized controlled trial 51 Chapter 4 Erythritol air-polishing in the surgical treatment of peri-implantitis; a 1-year randomized controlled trial 79 Chapter 5 Implant surface decontamination with phosphoric acid during surgical peri-implantitis treatment: a 3-month randomized controlled trial 109 Chapter 6 Influence of cervical crown contour on marginal bone loss around platform-switched bone-level implants: a 5-year cross- sectional study 127 Chapter 7 General discussion and conclusions 143 Addendum Summary 172 Samenvatting 176 Dankwoord 180 Curriculum Vitae 187 List of sponsors 189