Geert Kleinnibbelink

Post-Exercise Hypotension in Hypoxia 5 123 Table 2. Subject characteristics: baseline and post-training program Pre Post p-value Sex (m/f ) 10/5 Age (yr) 22.0±2.4 Height (cm) 172±11 Body Mass (kg) 71.2±11.7 70.3±12.3 0.17 BMI (kg/m2) 24.0±3.0 23.6±2.7 0.14 BSA (kg) 1.84±0.19 1.83±0.20 0.18 Resting HR (bpm) 77±10 66±6 <0.001 Resting SBP (mmHg) 118±4 113±9 0.02 Resting DBP (mmHg) 67±8 63±5 0.07 Resting MAP (mmHg) 84±6 80±6 0.03 VO2max (L/min) 3.7±0.7 3.9±0.8 <0.001 VO2max/kg (mL/min/kg) 52.1±7.1 55.7±7.3 <0.001 VE (L/min) 138±29 145±34 0.002 Hrmax (bpm) 199±8 195±6 0.008 Data are expressed as means±SD. m, male. f, female. BMI, body mass index. BSA, body surface area. HR, heart rate. SBP, systolic blood pressure. DBP, diastolic blood pressure. MAP, mean arterial pressure. VO 2 max, maximal oxygen uptake. VE, ventilation. Post-exercise blood pressure response in normoxia and hypoxia (acute study) HR during exercise was matched in exercise sessions in normoxia and in hypoxia (173±7 bpm, 172±7 bpm respectively, p=0.23). Body mass loss (hypoxia -410±320g vs. normoxia -410±199g, p=0.99) and water intake (hypoxia 373±228ml vs. normoxia 336±196ml, p=0.24) during exercise did not differ between both testing sessions. Mean distance covered during exercise was significantly higher in normoxia (6,655±1,266m) compared to hypoxia (5,797±1,112m, p < 0.001), whilst there was no significant difference in subjective ratings of perceived exertion (RPE normoxia 12.5±1.3, RPE hypoxia 13.3±1.5; p=0.07). SV was significantly decreased during recovery (p < 0.01), whilst this decline did not differ between hypoxia and normoxia (p=0.54) ( Table 3 )). Echocardiography showed a significantly higher CO during hypoxia compared to normoxia (P < 0.01), whilst no differences were found between rest and post-exercise (p=0.09) ( Table 3 ). TPR est was significantly lower during hypoxia compared to normoxia (P < 0.01), whilst no difference was found between baseline and recovery (P=0.83).