Geert Kleinnibbelink

Post-Exercise Hypotension in Hypoxia 5 127 Correlation of acute and chronic BP response (chronic study) During the prospective intervention part of our study, 6 participants dropped-out (motivational issues n=4; health problems unrelated to the study n=2). Participants completed on average 30±2 training sessions (94% adherence) at an average 83.5% of their maximumHR. These fifteen participants showed a significant increase in VO2max/kg (52.1 to 55.7 mL/min/kg, p < 0.001) (Table 2). Resting SBP, MAP and resting HR significantly decreased (118 to 113 mmHg, 84 to 80 mmHg and 78 to 66 bpm, respectively, p < 0.05) (Table 2). Resting DBP did not significantly change (67 to 63 mmHg, p=0.067) (Table 2). Pooled data derived from the experiments under normoxia and hypoxia indicate that the magnitude of PEH significantly correlatedwith the decrease in BP after 12-week of exercise training for DBP, SBP and MAP (Figure 3). When comparing data derived under normoxia versus hypoxia, no significant differences were observed in the correlation between PEH and resting BP (Fisher Z: SBP, p=0.22; DBP, p=0.35; MAP, p=0.65.