Geert Kleinnibbelink

RV Strain-Area Loop following Selexipag 8 175 with congenital heart disease) ( Table 1B, 1C ). The clinical responders decreased in NYHA classification and levels of NT-proBNP, while 6MWT increased. In contrary, the non- responders remained in the same NYHA classification, increased in NT-proBNP levels and decreased their 6MWT. With regards to the RV strain-area loop, RV longitudinal strain and uncoupling increased in the clinical responder group ( Table 1B , Figure 1B ), while in the clinical non-responders, RV longitudinal strain decreased, and uncoupling decreased and a leftward shift is present ( Table 1C , Figure 1C ). Conventional functional and structural (with exception of RVEDA) indices did not change in both clinical responders and non- responders ( Table 1B, 1C ).