Geert Kleinnibbelink

General Discussion 10 211 Obviously, the clinical relevance should be evaluated in a larger cohort consisting of PAH patients who start with or switch afterload reducing pharmacological treatment. At least, in combination with previous studies by Hulshof et al. 57, 58 , this thesis shows the potential of the RV strain-area loop in evaluating patients with PH ( Figure 5 ). Currently, methods to produce strain-area loops are based on manually drawing monoplane volumes. To incorporate the RV strain-area loop in daily clinical practice, development of currently used method to semi-automated strain-area loops would accelerate this process.