Geert Kleinnibbelink

TABLE OF CONTENTS Page Chapter 1 General Introduction and Outline of Thesis 11 Part l Right Ventricular Responses to Acute and Chronic Exercise 33 Chapter 2 Exercise-Induced Cardiac Fatigue after a 45-minute Bout of High-Intensity Running Exercise is not Altered under Hypoxia Journal of the American Society of Echocardiography, 2021 35 Chapter 3 Acute Exercise-Induced Changes in Cardiac Function Relates to Right Ventricular Remodelling Following 12-weeks Hypoxic Exercise Training Journal of Applied Physiology, 2021 65 Chapter 4 Exercise Training Induces Left- but not Right-Sided Cardiac Remodelling in Olympic Rowers International Journal of Sports Medicine, 2021 89 Chapter 5 The Acute and Chronic Effects of High-Intensity Exercise in Hypoxia on Blood Pressure and Post-Exercise Hypotension Medicine, 2020 115 Part ll Altered Haemodynamics and Exercise in Patients with Pulmonary Hypertension 137 Chapter 6 Prognostic Value of Right Ventricular Longitudinal Strain in Patients With Pulmonary Hypertension: a Systematic Review and Meta-Analysis European Heart Journal – Cardiovascular Imaging , 2019 139 Chapter 7 Effects of Preload Manipulation on Right Ventricular Contractility: Invasive Pressure-Area Loop versus Non-Invasive Strain-Area Loop Journal of the American Society of Echocardiography, 2021 163