Geert Kleinnibbelink

Chapter 1 General Introduction and Outline of Thesis 11
Chapter 2 Exercise-Induced Cardiac Fatigue after a 45-minute Bout of High-Intensity Running Exercise is not Altered under Hypoxia 35
Chapter 3 Acute Exercise-Induced Changes in Cardiac Function Relates to Right Ventricular Remodelling Following 12-weeks Hypoxic Exercise Training 65
Chapter 4 Exercise Training Induces Left- but not Right-Sided Cardiac Remodelling in Olympic Rowers 89
Chapter 5 The Acute and Chronic Effects of High-Intensity Exercise in Hypoxia on Blood Pressure and Post-Exercise Hypotension 115
Chapter 6 Prognostic Value of Right Ventricular Longitudinal Strain in Patients With Pulmonary Hypertension: a Systematic Review and Meta-Analysis 139
Chapter 7 Effects of Preload Manipulation on Right Ventricular Contractility: Invasive Pressure-Area Loop versus Non-Invasive Strain-Area Loop 163
Chapter 8 Right Ventricular Strain-Area Loop following 17-weeks of Selexipag in Pulmonary Arterial Hypertension Patients: an Exploratory Study 171
Chapter 9 Cardiac Rehabilitation is Associated with Lower 1-year All-Cause Mortality in Primary Pulmonary Hypertension 185
Chapter 10 General Discussion 197
Summary 224
Nederlandse Samenvatting 230
List of Abbreviations 236
Data Management 240
Dankwoord 242
Curriculum Vitae 248
List of Publications 250
RIHS PhD Portfolio 252

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