188 Chapter 7 3.4. Outcomes Figure 1 shows the mean PROMIS T-scores for boys with hemophilia and the Dutch reference group. In comparison with the Dutch reference data, boys with hemophilia reported more pain interference (P < .001, mean difference = 3.85, d = 0.60) and they scored worse on the domain Mobility (P < .001, mean difference = -6.33, d = -1.02). In contrast, boys with hemophilia scored better on the domain Peer Relationships. On the other domains, no differences were found between boys with hemophilia and the Dutch reference group. On the legacy instruments, boys with hemophilia scored a mean transformed total score of 20.2/24.5 (range, 0.4 – 91.6) on the Haemo-QoL (8-12 years and 13-17 years, respectively). On the PedHAL, boys with hemophilia scored a mean normalized score of 96.5 (range, 40-100) (Table 4). Figure 1. Mean PROMIS T-scores for boys with hemophilia and the Dutch reference group 3.5. Synthesis of the results Table 5 presents a synthesis of the results for the PROMIS pediatric measures and the legacy instruments.
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