Marga Hoogendoorn

111 Table 1. Baseline characteristics Patient factors: Patient type COVID-patients versus pneumonia patients Significance p-value Non-COVID patients versus non-pneumonia patients Significance p-value COVID-19 patients Pneumonia patients Non-COVID patients Non-pneumonia patients Number of patients – N (%) 218 (13.8 %) 147 (6.1%) 1,367 (86.2 %) 2,262 (93.9%) ICU admission type: Medical patients – N (%) Elective surgical patients – N (%) Urgent surgery patients – N (%) 217 (99.5) 1 (0.5) 0 (0) 147 (100) 0 (0) 0 (0) 1 1 - 447 (32.8 )* 678 (49.6 )* 239 (17.5) * 828 (36.6) * 1,188 (52.5) * 245 (10.8) * 0.019 0.100 <0.001 Comorbidities: Diabetes Mellitus – N (%) Renal insufficiency – N (%) Cardiovascular insufficiency – N (%) Respiratory insufficiency – N (%) 53 (24.3) 7 (3.2) 6 (2.8) 26 (11.9) 28 (19.0) 16 (10.9) 7 (4.8) 55 (37.4) 0.263 0.002 0.404 <0.001 251 (18.4) 57 (4.2) 76 (5.6) 145 (10.6) * 411 (18.2) * 147 (6.5) * 97 (4.3) 277 (12.2) * 0.890 0.005 0.098 0.151 Apache-APS score – Median (IQR) 50 (42 - 64) * 54 (44 – 68) 0.079 37 (27 - 51) 38 (27 - 55) * 0.079 Age – Median (IQR) 66 (58 - 74) 68 (59 - 76) 0.219 67 (58 - 73) 66 (56 – 73) 0.105 BMI – Median (IQR) 27.7 (25.2 - 30.2) 25.7 (23.0 – 29.8) 0.001 26.0 (23.2 - 29.4) 26.2 (23.5 – 29.6) 0.262 Mechanical ventilation in first 24 hours-N (%) 181 (83.0) 82 (55.8) <0.001 779 (57.0) 1,373 (60.7) 0.026 Mortality ICU-mortality - N (% In hospital mortality – N (%) 63 (28.9) * 85 (39.0) * 28 (19.0) 39 (26.5) 0.031 0.017 83 (6.1) 133 (9.7) 160 (7.1) * 201 (8.9) * 0.240 0.405 Length of ICU stay in days – Median (IQR) 14.0 (8.0 – 27.0) 3.9 (1.5 – 6.8) <0.001 0.9 (0.8 - 1.8) 0.9 (0.8 – 2.0) * 0.457 Nursing Activities Scores – Median (IQR) 55.2 (44.9 – 64.8) 50 (40.4 – 55.6) <0.001 42.6 (38.5 – 46.9) 42.9 (29.5 – 51.0) 0.037 * Statistically significant difference compared to baseline characteristics of other hospitals in the NICE database