Marga Hoogendoorn

59 Table 1. ICU characteristics Variable Included ICUs (n=7) All Dutch ICUs (n=84) Number of university hospitals (%) 1 (14%) 9 (11%) Number of teaching hospitals (%) 4 (57%) 23 (27%) Number of non-teaching hospitals (%) 2 (29%) 52 (62%) Median number of ICU beds per ICU (IQR) 13.0 [9.0, 17.0] 12.0 [8.0, 16.0] Table 2. Patient characteristics Variable Included patients in measurements All Dutch ICU patients Number of unique patients, N 287 100.145 Age, median [IQR] 66.0 [56.0-76.0] 66.0 [55.0-75.0] BMI, median [IQR] 26.0 [23.6-28.7] 25.9 [23.1-28.4] Admission type Medical, N (%) 121 (42.2) 51,290 (52.7) Surgical: urgent and elective, N (%) 151 (52.6) 45,905 (47.2) In-hospital mortality, N (%)* 85 (22.3) 13,017 (13.0) ICU LOS (in days), median [IQR]* 3.2 [0.9, 14.8] 1 [0.7-4.0] Comorbidities Acute renal failure, N (%)* 37 (12.9) 9211 (9.2) Cardiovascular insufficiency, N (%) 16 (4.2) 4257 (4.3) Chronic renal failure1, N (%) 25 (6.7) 7976 (7.9) Chronic respiratory insufficiency, N (%)* 7 (2.4) 4620 (4.6) Cirrhosis, N (%)* 1 (3.5) 1751 (1.7) COPD, N (%) 36 (12.5) 13,304 (13.3) Diabetes, N (%) 68 (17.8) 16,273 (16.2) Gastrointestinal bleeding, N (%) 2 (0.7) 2263 (2.3) Haematological malignancy, N (%) 6 (2.1) 2143 (2.1) Immunological insufficiency, N (%) 16 (5.6) 8290 (8.3) Neoplasm, N (%) 9 (3.1) 4506 (4.5) * Indicates a significant P value of <0.05. COPD = chronic obstructive pulmonary disease; IQR = interquartile range; LOS length of stay; 1 Chronic renal failure consists of chronic renal insufficiency and chronic dialysis