Addi van Bergen

Supplementary material chapter 2 167 11. Do the results of this study fit with other Yes Can’t tell No available evidence? 12. What are the implications of this study for practice? HINT: Consider • One observational study rarely provides sufficiently robust evidence to recommend changes to clinical practice or within health policy decision making • For certain questions observational studies provide the only evidence • Recommendations from observational studies are always stronger when supported by other evidence