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57 A COHORT STUDY ON FACTORS IMPAIRING SEMEN QUALITY IN TRANSGENDER WOMEN 4 Results of semen cryopreservation The median number of semen samples provided per person was 2.9 (SD 0.8), and the total number of provided samples was 323, divided over 3101 vials. The median semen parameters in our cohort were as follows: volume 2.4 ml (IQR 1.5-3.5), sperm concentration 27.5 million/ml (IQR 13.0-51.7), total sperm number 66.9 million (IQR 20.6-126.8), percentage of progressive motility 50.7 (IQR 38.8-60.3), and total motile sperm count 32.8 million (IQR 6.6-73.3). Semen quality was significantly lower than reported by the WHO for the general population (Figure 1). 10 Figure 1 . Box and whisker plots of semen analysis data. The data are semen volume, sperm concentration, total sperm number and percentage progressive motility from transgender women compared with World Health Organization (WHO) values for unscreened men from the general population. The boxes represent the quartiles and the lines within them are the medians; the whiskers extend from the 10th to the 90th centiles. * p-value < 0.05 using Wilcoxon signed-rank tests, for panel B, C, and D azoospermic transgender women were excluded from analysis.