Iris de Nie

58 C H A P T E R 4 Figure 2 shows the classification of semen quality in the study cohort according to the WHO reference values for human semen, the majority (60.2%) was classified as normozoospermia. 11 Post-thaw semen quality was available for 74 transgender women and the median TMSC was 0.5 million per vial (IQR 0.2-1.7). The majority of post-thawed samples was only suitable for invasive techniques, such as IVF (9.6%) or ICSI (67.1%), and in only 23.3% of samples the post-thaw quality was suitable for IUI. Characteristics of these 74 transgender women did not differ from the total cohort (data not shown). Figure 2 . Classification of semen quality in the study sample of 113 transgender women.The pie chart presents the descriptive diagnoses of transgender women according to World Health Organization (WHO) reference values for human semen. Influence of determinants on semen quality Logistic regression analyses showed no effect of age, BMI, smoking, cannabis use and medical history on the semen parameters. In addition, no significant association was found between previous hormone use and having impaired semen parameters. Drinking alcohol was associated with a normal semen volume, sperm concentration, total sperm number and total motile sperm count (Table 2).