Iris de Nie

93 HISTOLOGICAL STUDY ON THE INFLUENCE OF PUBERTY SUPPRESSION AND HORMONAL TREATMENT ON DEVELOPING GERM CELLS 6 Table 2. Results of histological and immunohistochemical analyses of orchiectomy specimens. Data are % (n) unless stated otherwise. Total (n=214) Adolescent Tanner stage 2-3 (n=29) Adolescent Tanner stage 4-5 (n=49) Adult (n=136) Cessation of GAHT (n=19) Continuation of GAHT (n=10) Cessation of GAHT (n=35) Continuation of GAHT (n=14) Cessation of GAHT (n=62) Continuation of GAHT (n=74) Spermatozoa 4.7 (10) 0 (0) 0 (0) 6 (2) 22 (3) 6 (4) 1 (1) Round spermatids 0.5 (1) 0 (0) 0 (0) 0 (0) 0 (0) 2 (1) 0 (0) Spermatocytes 21.5 (46) 21 (4) 40 (4) 31 (11) 14 (2) 23 (14) 15 (11) Spermatogonia 66.3 (142) 79 (15) 60 (6) 63 (22) 64 (9) 61 (38) 70 (52) No germ cells 7.0 (15) 0 (0) 0 (0) 0 (0) 0 (0) 8 (5) 14 (10) Mean Johnsen’s score - (SD) 2.5 (0.8) 2.6 (0.3) 2.7 (0.4) 2.8 (0.8) 3.2 (1.4) 2.5 (0.8) 2.3 (0.6) Hyalinization 75.2 (161) 47 (9) 40 (4) 63 (22) 79 (11) 76 (47) 92 (68) Lumen Open Half open Absent 8.4 (18) 25.2 (54) 66.4 (142) 0 (0) 26 (5) 74 (14) 0 (0) 10 (1) 90 (9) 3 (1) 31 (11) 66 (23) 22 (3) 14 (2) 64 (9) 18 (11) 26 (16) 56 (35) 4 (3) 26 (19) 70 (52)