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COLOFON This study was conducted within the Research Institute SHARE of the Graduate School of Medical Sciences, University Medical Center Groningen, University of Groningen and under auspices of the research program Public Health Research (PHR). The printing of this thesis was financially supported by the Graduate School of Medical Sciences, Research Institute SHARE, University Medical Center Groningen, and the University of Groningen. Printed by: Ridderprint Cover image: Marieke Nanninga in collaboration with ninamaakt ISBN: 978-94-034-0804-0 © 2018 Marieke Nanninga, the Netherlands All rights reserved. No part of this thesis may be reproduced or transmitted, in any form or by any means, without the written permission of the author.