Sanne de Bruin

110 Chapter 4 Results Patient characteristics During the study week, 49 patients were found eligible for study participation. One patient did not consent and was withdrawn from study participation. Therefore, data from 48 patients were obtained and analysed. The majority of the patients was male 33 (67%) and the age of the study population was 68.5 (53-72) years. During the first 24 hours, 27(56%) of the included patients received mechanical ventilation. Seventeen (35%) were admitted for treatment after cardiothoracic surgery, fifteen (31%) patients were admitted for non-surgical reasons. Other demographics, including reason of ad- mission are shown in table 1. Transfusion events In total 30 transfusion events and eight coagulation factor administrations were re- ported. Eight patients (17%) received one or more blood products and/or coagulation factors (table 2). Forty patients (83%) did not receive any blood product or coagulation factor. The majority of the products were ordered by a resident (85%) and administered in the ICU (95%) (table 3). The remaining two products were transfused in the operating theatre; one platelet and one RBC concentrate. Feasibility The study related workload per included patient was on average three hours, includ- ing obtaining informed consent and data collection. The most time-consuming part of data collection was the baseline data, in particular calculating the APACHE IV score and EuroSCORE. Median time of collecting the baseline characteristics was 11 (9-14) minutes. The daily CRF was completed most often (167 times) with a median time of 4 (3-5) minutes per form. Overall, the amount of missing data was limited (1.6%). In the demographics 0.8% of the data was missing, in all these cases the APACHE IV or EuroSCORE were missing. In the daily CRF, 1% of the data was missing: of this missing data the SOFA scores (40%), highest PT value (30%), and highest aPTT value (25%) were most frequently missing. The amount of missing data regarding transfusion events differed between the differ- ent blood products. Most frequently, data was missing in the coagulation factor form (11.9%), followed by plasma (3.1%), platelets (1.4%) and RBCs (1.0%) forms.