Sanne de Bruin

153 Storage of RBCs in PAGGGM improves metabolism after transfusion but has no effect on PTR Figure 1. Post transfusion recovery (PTR) is significantly different between 35 days stored SAGM and PAGGGM RBCs over time, but not on a specific time point (A). 35 days of storage in SAGM (B) and PAGGGM (C) results in decreased PTR compared with 2 days of storage in SAGM. Density of biotin did not affect the PTR of RBCs (D). The line plot indicates the median with 25 th and 75 th percentile of PTR over time, up to 90 days after transfusion. In addition to the PTR, which was calculated using the 10 minutes after transfusion ref- erence value, we also aimed to assess the clearance of RBCs in the first 10 minutes. We compared the ratio of fresh and stored RBCs in the RBC concentrate prior to transfusion with the ratio of these two populations in thewhole blood sample taken 10minutes after transfusion (supplemental figure S3 and S4). Six subjects, allocated to the SAGM group, received both 2-days stored RBCs and 35 days stored RBCs. In half of them (n=3) relative- ly more 2 days stored RBCs were cleared in the first 10 minutes, while in the other half more 35-days stored RBCs were cleared. nine subjects allocated to storage in PAGGGM received both RBC concentrates. In three subjects 2-days stored RBCs were cleared at 6