Sanne de Bruin

91 Transfusion practice in the bleeding critically ill; an international online survey – The TRACE-2 Survey Table S3. Difference between respondents with and without a hospital wide transfusion protocol (continued) No hospital-wide transfusion protocol (N=221) Hospital-wide transfusion protocol (N=180) P-value ICU-specific transfusion protocol 120(54%) 39(22%) p<0.001 Massive transfusion protocol 120(54%) 89(49%) 0.354 Table S4. Difference between respondents with and without an ICU-specific transfusion protocol No ICU-specific transfusion protocol (N= 242) ICU-specific transfusion protocol (N= 159) P-value Hemoglobin threshold in different subpopulations General ICU population 7[7-7] 7[7-7.5] 0.937 Trauma patients 7.05[7-8] 7.9[7-8] 0.315 Upper gastro-intestinal bleeding 7[7-8] 7[7-8] 0.542 Post cardiothoracic surgery 8[7.7-9] 8[8-9] 0.723 Obstetric patients 7[7-8] 7[7-8] 0.946 Patients with Sepsis 7[7-8] 7[7-8] 0.573 Patients on ECMO 8[7.2-9] 8[7-9] 0.026 Patients with TBI or stroke 8[7-9] 8[7-9] 0.305 Platelet count thresholds in different subpopulations General ICU population 50[20-50] 50[20-50] 0.861 Trauma patients 50[50-70] 50[50-75] 0.868 Upper gastro-intestinal bleeding 50[50-51.5] 50[50-70] 0.321 Post cardiothoracic surgery 50[50-80] 50[50-80.5] 0.901 Obstetric patients 50[50-70] 50[50-70] 0.673 3

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