125 Safety of HSG with oil-based contrast medium 5 Supplementary Table 6. (Continued) First author, year of publication Study type 1. Was the study’s target population a close representation of the national population in relation to relevant variables 2. Was the sampling frame a true or close representation of the target population? 3. Was some form of random selection used to select the sample, OR, was a census undertaken? 4. Was the likelihood of nonresponse bias minimal? 5. Were data collected directly from the subjects (as opposed to a proxy)? 6. Was an acceptable case definition used in the study? 7. Was the study instrument that measured the parameter of interest shown to have reliability and validity (if necessary)? 8. Was the same mode of data collection used for all subjects? 9. Were the numerator(s) and denominator(s) for the parameter of interest appropriate? 10. Summary of the overall risk of study bias: 0-3 Low risk, 4-6 moderate risk, 7-9 High risk. Lindequist, 1994 RCT Low risk Low risk Low risk Low risk Low risk Low risk High risk Low risk Low risk 1 Low risk Liu, 2010 Retrospective cohort Low risk Low risk Low risk Low risk Unclear Low risk High risk Unclear Low risk 3 Low risk Mackey, 1971 Retrospective cohort Low risk Low risk Low risk Low risk High risk High risk High risk High risk Low risk 4 Moderate risk Madsen, 1942 Retrospective cohort High risk Low risk Low risk Low risk Unclear Low risk High risk Unclear Low risk 4 Moderate risk Mekaru, 2008 Cohort not spec Low risk Low risk Unclear Low risk Low risk Low risk Low risk High risk Low risk 2 Low risk Nordio, 1938 Retrospective, cohort Unclear Unclear Unclear Low risk Unclear Low risk High risk Unclear Low risk 6 Moderate risk Norris, 1956 Cohort not spec Low risk Low risk Low risk Low risk Unclear Low risk High risk Unclear Low risk 3 Low risk Nugent, 2002 RCT Low risk Low risk Low risk Low risk Unclear High risk High risk Unclear Low risk 4 Moderate risk Nunley, 1987 Cohort not spec Low risk High risk Low risk Low risk Unclear Unclear High risk Unclear Low risk 5 Moderate risk Palmer, 1960 Cohort not spec Low risk Unclear Unclear Low risk Unclear Low risk High risk Unclear Low risk 5 Moderate risk
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