18 Chapter 1 complications after HSG with oil-based contrast and the potential differences with the safety profile of water-based contrast. It answers the question: What are the frequencies of complications during or after an HSG with oil-based contrast in infertile women and/ or their offspring? Another downside of HSG is the discomfort or pain that patients experience during the procedure. In chapter 6 we explore whether the use of virtual reality can improve the patient experience by distraction and relaxation. The research question in this chapter is: Is Virtual Reality an effective tool to reduce procedural pain during HSG? After several studies investigating HSG, we will also look into other visual tubal patency tests. We are performing a review comparing the diagnostic test accuracy of the most commonly used tubal patency tests: HSG, HyFoSy, HyCoSy, THL and MR-HSG. The protocol for this study, designed to answer the question ‘What is the diagnostic accuracy of the various types of visual tubal patency tests for diagnosing tubal occlusion?’ can be found in chapter 7. Finally, we conduct a national survey study among women whose fertility work-up or treatment or endometriosis treatment was paused due to the COVID-19 pandemic in 2020. With this survey we want to answer the following research question: What is the impact of the treatment pause on quality of life and quality of care of patients with infertility or endometriosis in the Netherlands? The results are presented in chapter 8.
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