CONTENTS Chapter 1 General introduction 7 Chapter 2 How long does the fertility-enhancing effect of hysterosalpingography with oil-based contrast last? Published in Reproductive BioMedicine Online 2020 doi: 10.1016/j.rbmo.2020.- 08.038 23 Chapter 3 Oil-based versus water-based contrast media for hysterosalpingography in infertile women of advanced age, with ovulation disorders or a high risk for tubal pathology: study protocol of a randomized controlled trial (H2Oil2 study) Published in BMC Women’s Health 2022 doi: 10.1186/s12905-022-01707-z 41 Chapter 4 Does the effectiveness of IUI in couples with unexplained subfertility depend on their prognosis of natural conception? A replication of the H2Oil study Published in Human Reproduction Open 2020 doi:10.1093/hropen/hoaa047 61 Chapter 5 Safety of HSG with oil-based contrast medium: a Systematic review Published in Reproductive BioMedicine Online 2021 doi: 10.1016/j.rbmo.2021- .03.014 79 Chapter 6 Virtual Reality for pain relief in hysterosalpingography Manuscript in preparation 129 Chapter 7 Visual tubal patency tests for tubal occlusion and hydrosalpinx Published in Cochrane Database of Systematic Reviews 2022 doi/10.1002/- 14651858.CD014968/full 153 Chapter 8 The impact of the COVID-19 pandemic on infertility patients and endometriosis patients in the Netherlands Published in reproductive BioMedicine Online 2021 https://doi.org/10.1016/j. rbmo.2021.06.001 1472-6483/ 171 Chapter 9 General discussion and future perspectives 191 Appendix Summary 208 Samenvatting 212 List of authors 216 List of publications 218 PhD portfolio 220 Dankwoord 222 About the author 227
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