52 Chapter 3 another well-known complication, the previously mentioned review described that in studies published in or after 1960, as antibiotics were not routinely used before, the frequency of infection was 0.55% after HSG with oil-based contrast and 0.35% after HSG with water-based contrast (18). The proposed study aims to provide information on the complication rate in a population of women that have a higher risk for tubal pathology (because of a previous infection, pelvic surgery or endometriosis). Complications will be reported systematically. This multicentre RCT will establish whether, for women that are 39 years or older, women with ovulation disorders, and women who have a high risk for tubal pathology, there is a fertility enhancing effect of tubal flushing at HSG with oil-based contrast during fertility work-up and if this is cost-effective.
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