Aernoud Fiolet

124 Chapter 5 Figure 1. Enrollment, Randomization, and Follow-up. Premature permanent discontinuation of colchicine or placebo was determined to have occurred if colchicine or placebo was permanently discontinued more than 30 days before the occurrence of a primary end-point event, the occurrence of noncardiovascular death, or the regular end-of-trial date, whichever came first.