Aernoud Fiolet

145 Colchicine in Patients with Chronic Coronary Disease Figure S2 Subgroup Analysis of the Primary End Point. The primary end point was cardiovascular death, myocardial infarction, ischemic stroke or ischemia-driven coronary revascularization. * Stage 1 refers to an estimated glomerular filtration rate of ≥ 90 ml/min per 1.73m² (normal or high), stage 2 to 60-89 ml/min per 1.73 (mildly decreased), and stage 3a to 45-59 ml/min per 1.73m² (mildly to m oderately decreased). Stages are based on the Clinical Practice Guideline of Kidney Disease: Improving Global Outcomes (KDIGO). 2 † Statin intensity was categorized in accordance with the guidelines of the American College of Cardiology and American Heart Association. 3