Aernoud Fiolet

195 The efficacy and safety of low-dose colchicine in patients with coronary disease Supplementary Table S1A: Composite end points and definitions End point Reference Primary composite end point LoDoCo2 Cardiovascular death, spontaneous (non-procedural) myocardial infarction, ischemic stroke 1 COPS Cardiovascular death, myocardial infarction, non-cardioembolic ischemic stroke 2 COLCOT Cardiovascular death, resuscitated cardiac arrest, myocardial infarction, stroke 3 LoDoCo Cardiovascular death, spontaneous (non-procedural) myocardial infarction, ischemic stroke 4 Secondary composite end point LoDoCo2 Cardiovascular death, spontaneous (non-procedural) myocardial infarction, ischemic stroke, ischemia-driven coronary revascularisation. 1 COPS Cardiovascular death, myocardial infarction, non-cardioembolic ischemic stroke, ischemia-driven urgent revascularisation 2 COLCOT Cardiovascular death, resuscitated cardiac arrest, myocardial infarction, stroke, or urgent hospitalisation for angina leading to coronary revascularisation 3 LoDoCo Cardiovascular death, spontaneous (non-procedural) myocardial infarction, ischemic stroke, ischemia-driven coronary revascularisation. 4