Aernoud Fiolet

200 Chapter 7 507 citations identified 200 123 128 56 92 415 abstracts screened 343 studies excluded 7 Non-human studies 199 No randomized controlled trial 66 No established atherosclerosis 67 No (long-term) colchicine administration 4 No cardiovascular events reported 72 full texts screened 57 studies excluded 16 No randomized controlled trial 23 No established atherosclerosis 16 No (long-term) colchicine administration 2 No cardiovascular events reported 10 trials in progress 5 unique trials included - LoDoCo 2013 - Deftereos 2013 - COLCOT 2019 - COPS 2020 - LoDoCo2 2020 Screening Eligibility Included Identification Key Search terms in Pubmed ("Atherosclerosis") in Embase AND ("Colchicine") AND in CENTRAL ("Randomized Trial") in Clinicaltrials.gov Duplicates Removed Supplementary Figure S1: PRISMA search strategy