Aernoud Fiolet

204 Chapter 7 16 Supplementary Appendix Supplementary Figure S4A: Sensitivity analysis of meta-analysis of colchicine trials excluding the non- placebo controlled trial LoDoCo for the primary and secondary composite end points Composite of myocardial infarction, stroke, or cardiovascular death Composite of myocardial infarction, stroke, coronary revascularisation, or cardiovascular death Pooled relative risks and 95% confidence intervals for the composite of myocardial infarction, stroke, or cardiovascular death (upper panel) and for the composite of myocardial infarction, stroke, coronary revascularisation, or cardiovascular death (lower panel) in patients treated with colchicine as compared to placebo or no colchicine excluding the non-placebo controlled trial LoDoCo. Abbreviations: CI, confidence interval. GIV, generic inverse variance. Supplementary Figure S4A: Sensitivity analysis of meta-analysis of colchicine trials excluding the non-placebo controlled trial LoDoCo for the primary and secondary composite end points Pooled relative risks and 95% onfidence intervals for the composite of myocardial infarction, strok , or cardi vascular death (upper pane ) and f r the composite f myocardial infarction, stroke, coronary revascularisation, or cardiovascular death (lower panel) in patients tr ated with colchicine as compared to placebo or no colchicine excluding the non-placebo controlled trial LoDoCo. Abbreviations: CI, confidence interval. GIV, generic inverse variance.