Aernoud Fiolet

245 Short-term effect of low-dose colchicine on biomarkers Table 2. Inflammatory markers and lipids. Inflammatory Markers Unit Visit 1 Visit 2 Mean or median of differences 95% CI P-value % change from baseline Interleukin-6 ng/L median 2.51 2.22 -0.36 (-0.70 to -0.01) 0.04 -16% hs-CRP mg/L median 4.40 2.33 -1.66 (-2.17 to -1.22) <0.01 -40% Lipids Visit 1 Visit 2 Mean or median of differences 95% CI P-value % change from baseline Total Cholesterol mmol/l Mean 4.07 3.96 -0.07 (-0.16 to 0.01) 0.091 NS HDL Cholesterol mmol/l Mean 1.16 1.13 -0.03 (-0.05 to -0.01) <0.01 -3% LDL cholesterol mmol/l Mean 2.38 2.24 -0.07 (-0.13 to 0.00) 0.04 -2% Triglycerides mmol/l Mean 2.04 2.13 0.08 (-0.05 to 0.21) 0.21 NS Abbreviations: hs-CRP, high sensitive C Reactive Protein; IL, interleukin; IQR, interquartile range.