Aernoud Fiolet

246 Chapter 9 Table 3. Differences in inflammatory markers between subgroups Clinical subgroup Visit 1 hs-CRP [IQR] Visit 2 hs-CRP [IQR] P-value for interaction Visit 1 IL6 [IQR] Visit 2 IL6 [IQR] P-value for interaction Diabetes 4.46 [2.56-8.42] 2.28 [1.23-5.53] 0.329 2.96 [1.97-4.72] 3.09 [1.75-3.67] 0.743 No diabetes 4.29 [2.83-6.86] 2.34 [1.42-3.77] 2.40 [1.49-4.10] 2.13 [1.38-3.39] P-value for within differences 0.723 0.896 0.147 0.115 Active smoking 5.08 [2.83-8.33] 3.10 [2.05-5.83] 0.893 2.45 [1.50-3.74] 2.48 [1.90-4.62] 0.084 No active smoking 4.27 [2.76-6.86] 2.27 [1.41-3.56] 2.62 [1.59-4.56] 2.17 [1.37-3.25] P-value for within differences 0.256 0.087 0.753 0.160 Obesity 4.45 [2.67-7.10] 2.55 [1.52-4.48] 0.156 2.70 [1.76-4.53] 2.30 [1.45-3.58] 0.063 No obesity 3.63 [2.86-4.99] 1.84 [0.69-2.46] 1.76 [0.97-3.44] 1.76 [0.82-3.01] P-value for within differences 0.304 0.010 0.060 0.173 Statin 4.29 [2.67-7.08] 2.31 [1.38-3.91] 0.097 2.64 [1.55-4.53] 2.26 [1.45-3.58] 0.483 No statin 4.69 [3.29-6.27] 2.72 [2.02-4.21] 1.97 [1.64-3.44] 1.77 [0.57-2.69] P-value for within differences 0.551 0.274 0.403 0.145 Abbreviations: CI, confidence interval; eGFR, estimated glomerular filtration rate; MCV, mean corpuscular volume; NS, not significant.