Aernoud Fiolet

247 Short-term effect of low-dose colchicine on biomarkers Table 4. Haematology and renal function. Haematology Unit Visit 1 Visit 2 Mean or median of differences 95% CI P-value % change from baseline Hemoglobine (mmol/L) Mean 9.08 9.09 0.02 (-0.05 to 0.09) 0.59 NS Hematocrit L/L Mean 0.44 0.44 0.00 (-0.01 to 0.00) 0.28 NS Erytrocytes (x 10¹²/L) Mean 4.87 4.87 0.00 (-0.04 to 0.04) 0.93 NS MCV (fl) Mean 91.47 91.17 -0.35 (-0.68 to -0.03) 0.03 0% Leukocytes (x 10 9 /L) Median 6.99 6.62 -0.47 (-0.74 to -0.19) <0.01 -7% Trombocytes (x 10 9 /L) Median 237.50 231.00 -11.50 (-16.50 to -6.50) <0.01 -4% Renal function Unit Visit 1 Visit 2 Mean or median of differences 95% CI P-value % change from baseline eGFR (ml/min/1,73m²) Mean 76.81 74.99 -1.94 (-3.46 to -0.42) 0.01 -2% Creatinine (µmol/L) Mean 87.90 89.53 1.69 (0.10 to 3.28) 0.04 1% Abbreviations: CI, confidence interval; eGFR, estimated glomerular filtration rate; MCV, mean corpuscular volume; NS, not significant.