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251 Short-term effect of low-dose colchicine on biomarkers ACKNOWLEDGMENTS The help of the research personnel (Ms Hanneke Bakker, Ms Petra Bunschoten, Ms Marjan van Doorn, Ms Coriet Hobé, Ms Hilde Giezen) at the involved sites and the laboratory staff (Ms Marjet Klein Avink) was highly appreciated. Funding Statement This work was supported by a governmental grant from The Netherlands Organisation for Health Research and Development [grant number 848015014]. The drug was supplied free of charge by TioPharma (Oud-Beijerland, the Netherlands). The funders and drug supplier had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. There are no conflicts of interests by the authors.

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