Aernoud Fiolet

329 Text-mining in electronic healthcare records can be used for screening and data collection SUPPLEMENTARY MATERIAL 1a. Search query used to identify potential eligible patients Eligibility criteria Search terms Appointment cardiology outpatient department during recruitment periode Appointment cardiology department between [START_ RECRUITMENT] and [END_ RECRUITMENT] Inclusion criteria 1. Are aged >35 and <82 years, 2. Have proven coronary artery disease; as evidenced by coronary angiography, CT coronary angiography or a Coronary Artery Calcium Score (Agatston score >400). Individuals with a history of bypass surgery are only eligible if they have undergone coronary artery bypass surgery more than 10 years before, or have angiographic evidence of graft failure or have undergone percutaneous intervention since their bypass surgery. Age >35 and <82 years “Percutane Coronaire Interventie” OR "Percutaneous Coronary Intervention" OR "Percutaneous Coronary Revascularization" OR "pci" OR "bms" OR "bvs" OR "des" OR "stent" OR "dotter" OR "CT coronary angiography" OR “Agatston” OR ((“CABG” OR “Coronary artery bypass”) AND NOT < 6 months 3. Have been clinically stable for at least six months. Are aged >35 and <82 years Exclusion criteria 1. Women who are pregnant, breast feeding or may be considering pregnancy during the study period, NOT (“zwangerschap” OR “zwanger" OR “borstvoeding”) 2. Have renal impairment as evidenced by a serum creatinine >150 μmol /l or estimated glomerular filtration rate (eGFR) <50mL/ min/1.73m2, MEASUREMENT eGFR <50 OR serum creatinine >150 3. Have severe heart failure – systolic or diastolic NewYork Heart Association Functional classification 3 or 4, NOT (“NYHA III” OR “NYHA IV”) 4. Have moderate or severe valvular heart disease considered likely to require intervention, NOT (“valvular heart disease OR “hartklep ziekten”) 5. Are dependent or frail or have a life expectancy < five years, NOT (“frail” OR “beperkte levensverwachting”) 6. Have peripheral neuritis, myositis or marked myo- sensitivity to statins, NOT (“neuritis” OR “myositis” OR “myo-sensitivitis” 7. Are already taking long term colchicine therapy for any other reason, NOT DRUG “Colchicine” 8. Are currently enrolled in a competing trial. NOT [RUNNING TRIALS]