Table of Contents
I
421
Aernoud Fiolet
Chapter 1 General introduction and thesis outline
11
Chapter 2 Viewing Atherosclerosis through a Crystal Lens: How the Evolving Structure of Cholesterol Crystals in Atherosclerotic Plaque Alters its Stability
51
Chapter 3 Colchicine in Stable Coronary Artery Disease
73
Chapter 4 The effect of low-dose colchicine in patients with stable coronary artery disease: The LoDoCo2 trial rationale, design, and baseline characteristics
93
Chapter 5 Colchicine in Patients with Chronic Coronary Disease
117
Chapter 6 Reply. Colchicine in Patients with Chronic Coronary Disease
161
Chapter 7 The efficacy and safety of low-dose colchicine in patients with coronary disease: a systematic review and meta-analysis of randomised trials
173
Chapter 8 Colchicine in chronic coronary disease in relation to history of acute coronary syndrome
215
Chapter 9 Short-term effect of low-dose colchicine on inflammatory biomarkers, lipids, blood count and renal function in chronic coronary artery disease and elevated high-sensitivity C-reactive protein
233
Chapter 10 Colchicine Attenuates Inflammation Beyond the Inflammasome in Chronic Coronary Artery Disease. A LoDoCo2 Proteomic Substudy
257
Chapter 11 Colchicine reduces extracellular vesicle NLRP3 inflammasome protein levels in vitro and in vivo in chronic coronary disease: a LoDoCo2 substudy
267
Chapter 12 Predictors of early intolerance to low-dose colchicine in patients with coronary disease
291
Chapter 13 Text-mining in electronic healthcare records can be used as efficient tool for screening and data collection in cardiovascular trials: a multicenter validation study
313
Chapter 14 Accuracy of using routinely collected electronic healthcare data to identify major cardiovascular endpoints in randomized controlled trials: a multicenter validation study
337
Chapter 15 Clinical implications and future perspectives
359
Chapter 16 Summary
381
Summary in Dutch
391
List of publications
399
Acknowledgements
405
About the author
419
Made with FlippingBook
RkJQdWJsaXNoZXIy ODAyMDc0