Table 2: Ratings of on‐site investigator (OSI) and treating physician (TP) for 3CAT and WHOCAT, overall. 3CAT Ratings of on‐site investigator (OSI) Definitely Possibly Did not contribute Total % Ratings of treating physician (TP) Definitely 101 11 1 113 39 Possibly 27 92 21 140 48 Did not contribute 0 9 29 38 13 Total % 128 44 112 38 51 18 291 100 WHOCAT Ratings of on‐site investigator (OSI) Sole cause Part of causal sequence Contribut. but unrelated Did not contribute Unknown Missing Total % Ratings of treating physician (TP) Sole cause 14 3 2 1 1 0 21 7 Part of causal sequence 9 138 10 3 0 0 160 55 Contributory but unrelated 1 15 25 15 0 0 56 19 Did not contribute 1 7 5 35 0 0 48 16 Unknown 0 0 1 1 1 0 3 1 Missing 0 0 0 0 0 3 3 1 Total (%) 25 9 163 56 43 15 55 19 2 1 3 1 291 100 Overall, antimicrobial treatment was considered adequate in 80% of the cases (210/262 for TP, 210/263 for OSI), with high agreement on the perceived adequacy (kappa 0.87, 95% CI: 0.80‐0.95) when including the cases where the adequacy of antimicrobial treatment was classified as unknown. In cases of HAI with organisms with the AMR phenotypes under surveillance, the antimicrobial treatment was less often evaluated as adequate (71% (69/ 97)) compared to HAI with an organism without any of the AMR phenotypes under surveillance (91% (67/74)). The contribution of AMR was less often classified as possible or definite when the antimicrobial treatment was considered adequate than when it was inadequate (33% (50/153 for TP; 51/154 for OSI) adequate vs 25/31 and 25/28 inadequate for TP and OSI; p<0.0001). 6 115 Mortality review reproducibility study
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