Chapter 7 Prevention of hospital infections by intervention and training (PROHIBIT): results of a pan‐European cluster‐ randomized multicentred study to reduce central venous catheter‐related bloodstream infections Tjallie van der Kooi1, Hugo Sax2,3, Didier Pittet3, Jaap van Dissel1, Birgit van Benthem1, Bernhard Walder3, Vanessa Cartier3, Lauren Clack2, Sabine de Greeff1, Martin Wolkewitz4, Stefanie Hieke4, Hendriek Boshuizen1, Jan van de Kassteele1, Annemie Van den Abeele5, Teck Wee Boo6, Magda Diab‐Elschahawi7, Uga Dumpis8, Camelia Ghita9, Susan Fitzgerald10, Tatjana Lejko11, Kris Leleu5, Mercedes Palomar Martinez12, Olga Paniara13, Márta Patyi14, Paweł Schab15, Annibale Raglio16, Emese Szilágyi17, Mirosław Ziętkiewicz18, Albert W. Wu19, *Hajo Grundmann4,20; *Walter Zingg3,21, on behalf of the PROHIBIT consortium. 1 RIVM National Institute for Public Health and the Environment, 3720 BA, Bilthoven, the Netherlands 2 Division of Infectious Diseases and Hospital Epidemiology, University Hospital of Zurich, University of Zurich, 8006, Zurich, Switzerland 3 Infection Control & World Health Organization Collaborating Center on Patient Safety, The University of Geneva Hospitals and Faculty of Medicine, 1211, Geneva, Switzerland 4 University of Freiburg, 79085, Freiburg, Germany 5 AZ Sint‐Lucas hospital, 9000, Ghent, Belgium 6 University Hospital Galway, Galway, H91 YR71, Ireland 7 Medical University of Vienna, 1090, Vienna, Austria 8 Pauls Stradins Clinical University Hospital, Riga, LV‐1002, Latvia 9 Department of Infection control, Institute for emergency cardiovascular diseases "Prof. C.C. Iliescu", Bucharest, 022328, Romania 10 St. Vincent’s University Hospital, Dublin, D04 Y8V0, Ireland 11 University Medical Center Ljubljana, 1000, Ljubljana, Slovenia 12 Arnau de Vilanova University Hospital, 25198, Lleida & Vall d’Hebron University Hospital and Universitat Autónoma, 08035, Barcelona, Spain 13 Evanggelismos hospital, Athens, 106 76, Greece 14 Bács‐Kiskun County Teaching Hospital, Kecskemét, 6000, Hungary 15 Hospital of Silesia, 43‐400, Cieszyn, Poland 16 Papa Giovanni XXIII Hospital, 24127, Bergamo, Italy 17 Office of the Chief Medical Officer & Szent János Hospital, Budapest, 1125, Hungary 18 John Paul II Hospital, Kraków, 30‐001, Poland 19 John Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205, USA 20 University Medical Center Groningen, 9713 GZ, Groningen, the Netherlands 21 Imperial College London, London, SW7 2AZ, United Kingdom *loco equo PROHIBIT Consortium: PROHIBIT Study Group: Pittet D (principaI investigator), Zingg W (coordinator), Ahmad R, Allegranzi B, Cookson B, Dettenkofer M, Gastmeier P, Grundmann H, Hansen S, Heczko PB, Holmes A, Kyratsis Y, Magiorakos A, Martin M, Richet H, Sax H, Szilágyi E, van Benthem B, van der Kooi T, Wu AW. Intensive Care Medicine 2018(44): 48‐60
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