Table 1: Patient and central venous catheter characteristics at baseline and intervention, stratified by study arm HH intervention only CVC intervention only Both interventions Baseline Intervention p‐value Baseline Intervention p‐value Baseline Intervention p‐value CRBSI per 1000 CVC days (95% CI) 2.0 (1.4 –2.6) 0.9 (0.6 – 1.2) 0.0004 1.4 (1.1 – 1.8) 0.8 (0.6 – 1.0) 0.0002 5.3 (4.3 – 6.3) 1.3 (1.0 – 1.7) <0.0001 Dwell time in days (median (IQR) 6 (3 – 10) 7 (4 – 9) 0.41 5 (3 – 9) 5 (3 – 9) 0.46 6 (3 – 11) 5 (2 – 10) <0.0001 N % N % p‐value N % N % p‐value N % N % p‐value Patients 1506 2476 6090 9454 2004 3818 CVCs 2898 5273 7664 12061 2669 5266 CVC‐days 21854 38730 5533 0 86363 21099 39001 CRBSIs 43 34 78 65 111 51 Sex Male Female 1856 1042 64.0 36.0 3361 1912 63.7 36.3 0.78 5126 2538 66.9 33.1 7702 4359 63.9 36.1 <0.0001 1619 1050 60.7 39.3 3261 2005 61.9 38.1 0.27 Age (years) < 30 30‐49 50‐69 ≥ 70 227 438 1130 1103 7.8 15.1 39.0 38.1 331 838 2150 1954 6.3 15.9 40.8 37.1 0.03 273 864 3443 3084 3.6 11.3 44.9 40.2 393 1431 5350 4887 3.3 11.9 44.4 40.5 0.37 112 411 1208 938 4.2 15.4 45.3 35.1 133 822 2619 1692 2.5 15.6 49.7 32.1 <0.0001 Type of admissiona Medical Surgical Unscheduled surgical 1587 744 567 54.8 25.7 19.6 2779 1068 1426 52.7 20.3 27.0 <0.0001 2200 4438 1026 28.7 57.9 13.4 3384 6893 1784 28.1 57.2 14.8 <0.02 1549 608 512 58.0 22.8 19.2 2091 1993 1182 39.7 37.8 22.4 <0.0001
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