Table S2: CRBSI incidence densities for patient and central venous catheter (CVC) characteristics, based on the entire study duration CVC (N) CVC‐days (N) CVC‐days (%) CRBSI (N) Incidence density (N/1000 CVC‐days) 95% CI Total 35831 262377 100.0 382 1.5 1.3 – 1.6 Sex Male Female 22925 12906 165983 96394 63.3 36.7 232 150 1.4 1.6 1.2 – 1.6 1.3 – 1.8 Age < 30 years 30‐49 50‐69 ≥ 70 1469 4804 15900 13658 11403 37213 113890 99871 4.3 14.2 43.4 38.1 12 59 170 141 1.1 1.6 1.5 1.4 0.6 – 1.9 1.2 – 2.0 1.3 – 1.7 1.2 – 1.7 Type of admissiona Medical Surgical Unscheduled surgical 13590 15744 6497 116732 91365 54280 44.5 34.8 20.7 207 85 90 1.8 0.9 1.7 1.5 – 2.0 0.8 – 1.2 1.3 – 2.0 APACHE II scoreb < 10 10‐19 20‐29 ≥ 30 NA 1971 4133 5116 1692 22919 10866 29492 40683 13803 167533 4.1 11.2 15.5 5.3 63.9 18 79 70 19 196 1.7 2.7 1.7 1.4 1.2 1.0 – 2.6 2.1 – 3.3 1.4 – 2.2 0.9 – 2.2 1.0 – 1.3 SAPS II scorec < 20 20‐39 40‐59 ≥ 60 NA 4529 3983 2263 894 24162 19300 28842 23674 8847 181714 7.4 11.0 9.0 3.4 69.3 6 25 39 24 288 0.3 0.9 1.6 2.7 1.6 0.1 – 0.7 0.6 – 1.3 1.2 – 2.3 1.8 – 4.0 1.4 – 1.8
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