CVC (N) CVC‐days (N) CVC‐days (%) CRBSI (N) Incidence density (N/1000 CVC‐days) 95% CI Type of CVC CVC Swan‐Ganz 34419 1412 255985 6392 97.6 2.4 376 6 1.5 0.9 1.3 – 1.6 0.4 – 2.1 Lumen Multi Single 34286 1545 250125 12252 95.3 4.7 359 23 1.4 1.9 1.3 – 1.6 1.2 – 2.8 Indication Antibioticse No antibioticse Blood products No blood products Dialysis No dialysis TPNf No TPNf Other indicationsg 28020 7342 5223 30608 3637 32194 6337 27983 29376 206018 54043 41369 221008 32081 230296 69087 180991 206227 79.2 20.8 15.8 84.2 12.2 87.8 27.6 72.4 87.5 323 52 90 292 36 346 106 187 319 1.6 1.0 2.2 1.3 1.1 1.5 1.5 1.0 1.5 1.4 – 1.7 0.7 – 1.3 1.8 – 2.7 1.2 – 1.5 0.8 – 1.6 1.4 – 1.7 1.3 – 1.9 0.9 – 1.2 1.4 – 1.7 CVC dwell‐timeh 1‐4 days 5‐9 10‐19 ≥ 20 15556 11478 6973 1824 124743 75081 46720 15833 53 111 167 51 0.4 1.5 3.6 3.2 0.3 – 0.6 1.2 – 1.8 3.1 – 4.2 2.4 – 4.2 a according to the SAPS II criteria: medical: no surgery within 1 week of admission to ICU; scheduled surgical: surgery was scheduled at least 24 hours in advance +/‐ 7 days intensive care unit admission; unscheduled surgical: patients added to the operating room schedule within 24 hours of the operation. b APACHE=Acute Physiology and Chronic Health Evaluation; on first ICU admission c SAPS=Simplified Acute Physiology Score; on first ICU admission d including subsequent ICU stays (max. 3) until insertion e data of first two months of one hospital excluded because of invalid or missing data f one hospital excluded because of invalid or missing data
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