g data of first year of three hospitals and of first four months of another hospital excluded because of different interpretation h number of CVC days per category acc. to McLaws[1] Table S3. APACHE II scores and SAPS II scores at baseline and intervention, stratified by study arm HH intervention only CVC intervention only Both interventions Baseline Intervention Baseline Intervention Baseline Intervention N % N % p‐value N % N % p‐value N % N % p‐value APACHE II scoreb <10 48 3.2 59 2.4 <0.0001 72 1.2 140 1.5 <0.0001 245 12.2 953 25.0 <0.0001 10‐19 182 12.1 306 12.4 <0.0001c 461 7.6 490 5.2 <0.0001c 461 23.0 894 23.4 <0.0001c 20‐29 120 8.0 358 14.5 1283 21.1 1028 10.9 249 12.4 457 12.0 ≥ 30 49 3.3 164 6.6 240 3.9 173 6.8 90 4.5 238 6.2 missing 1107 73.5 1589 64.2 4034 66.2 7623 80.6 959 47.9 1276 33.4 SAPS II scorea <20 30 2.0 38 1.5 <0.0001 1611 26.5 2532 26.8 <0.0001 5 0.2 2 0.05 <0.0001 20‐39 181 12.0 200 8.1 0.74c 927 15.2 1668 17.6 0.02c 28 1.4 22 0.6 0.88c 40‐59 159 10.6 161 6.5 356 5.8 619 6.5 123 6.1 92 2.4 ≥ 60 40 2.7 50 2.0 110 1.8 152 1.6 121 6.0 86 2.3 missing 1096 72.8 2027 81.9 3086 50.7 4483 47.4 1727 86.2 3616 94.7 a APACHE=Acute Physiology and Chronic Health Evaluation; p‐value based on non‐missing values; on first ICU admission b SAPS=Simplified Acute Physiology Score; p‐value based on non‐missing values; on first ICU admission c p‐value when missing values excluded
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