Table S4 CVC utilization ratios (CVC daysa/ICU patient‐days) for all three study arms together and per study arm CVC utilization ratio 2011 2012 2013 P‐valueb All three study arms together 88.3 80.7 73.5 0.01 CVC intervention arm 95.2 86.4 78.1 0.01 HH intervention arm 89.1 79.2 75.8 0.18 Both interventions 76.3 69.9 61.5 0.05 a for the CVC utilization ratio multiple CVCs on one day were counted as one CVC day b based on the yearly change, in linear regression Table S5: Individual central venous catheter (CVC) observation form elements (mean score), stratified by intervention arm HH intervention CVC intervention Both interventions Observation form elements BL INT P‐value BL INT P‐value BL INT P‐value Work organization All material prepared for use 96.5 97.7 0.30 90.6 97.8 <0.0001 100.0 99.6 0.33 Trash bin in place 95.2 95.7 0.75 67.7 94.3 <0.0001 96.8 99.5 <0.0001 Operator never leaves the patient zone 96.9 95.7 0.41 87.7 97.0 <0.0001 98.2 98.2 1.00 Patient preparation Hand hygiene before patient contact 57.7 85.5 <0.0001 48.9 86.4 <0.0001 93.0 98.7 <0.0001 Patient’s hair is covered by a cap 15.4 40.5 <0.0001 63.1 87.7 <0.0001 14.9 86.3 <0.0001 Skin antisepsis All medical devices for skin antisepsis are sterile 61.7 86.7 <0.0001 94.3 99.8 <0.0001 96.2 99.4 <0.0001 Use of alcohol‐based chlorhexidine for skin antisepsisa 56.8 79.4 <0.0001 58.3 77.6 <0.0001 20.3 93.4 <0.0001 Use of sterile gloves for skin antisepsis 63.0 85.7 <0.0001 87.4 99.0 <0.0001 92.1 98.4 <0.0001 Skin antisepsis follows a correct technique 50.7 86.5 <0.0001 32.0 96.8 <0.0001 89.8 87.8 0.27 Skin antisepsis performed before applying MSB 18.4 41.3 <0.0001 58.7 93.8 <0.0001 95.1 98.4 0.0004
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