These 66 hospitals reported data on 62,862 CVCs and 423,316 CVC days for 49,388 patients, with 799 infections. Of the 66 hospitals in the CRBSI surveillance, 56 (84.8%) recorded bundle (non)compliance for 80% or more of the CVCs, for one to nine years with a median of four years (IQR 3‐6), summing up to 240 of the total of 324 hospital years (74.1%) in the CRBSI surveillance (Supplementary Table S1 gives the yearly participation per hospital). In these 240 hospital years, data were reported on 43,262 CVCs and 291,610 CVC days for 31,687 patients, with 507 infections (62.9% microbiologically confirmed CRBSI, 3.9% CRBSI category 1, 16.0% CRBSI category 2, 15.8% CRBSI category 3 and 1.4% CRBSI category 4). Figure 1: Central venous catheter‐related bloodstream infection (CRBSI) incidence and number of hospitals per calendar year. CRBSI incidence density overall, in and outside the ICU, overall and for those hospitals with >80% bundles recorded in a year. The number of hospitals participating in the national CRBSI surveillance per year and the number of hospitals that recorded bundle compliance in > 80% of the CVCs (evaluated per year). Hospital years with ≥80% bundle recordings Patient and CVC characteristics Table I shows the patient and CVC characteristics. Apart from sex, all patient and CVC characteristics fluctuated significantly over the years. The percentage of patients outside the ICU increased and the proportion of patients between 18 and 45 years decreased 0 5 10 15 20 25 30 35 40 45 50 0 1 2 3 4 5 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 Number of participating hospitals CRBSI incidence density per 1000 catheter days No of hospitals in CRBSI surveill. No of hospitals with >80% bundle rec. CRBSI incid CRBSI in hospitals >80% bundle reg. CRBSI in ICU CRBSI in ICU in hospitals >80% bundle reg. CRBSI non‐ICU CRBSI non‐ICU in hospitals >80% bundle reg. 220 Chapter 9
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