Patients Perc. of patients Ventilator days Perc. of ventilator days Number of VAPs Perc. patients with VAP Incidence density per 1000 ventilator days HR (95% CI) p‐value LOS (before ventilation) 0 days 322 34.3 2553 32.4 34 10.6 13.3 Ref 1 168 17.9 1446 18.4 17 10.1 11.8 0.98 (0.54 – 1.78) 0.96 2 94 10.0 791 10.0 10 10.6 12.6 0.99 (0.49 – 2.01) 0.97 3‐5 132 14.0 1175 14.9 6 4.5 5.1 0.38 (0.16 – 0.92) 0.03 6‐10 104 11.1 834 10.6 7 6.7 8.4 0.61 (0.27 – 1.39) 0.24 >10 120 12.8 1073 13.6 7 5.8 6.5 0.55 (0.25 – 1.18) 0.13 LOS_IC (before ventilation) 0 days 746 79.4 5953 75.6 64 8.6 10.8 Ref 1 113 12.0 1109 14.1 12 10.6 10.8 1.02 (0.55 – 1.91) 0.94 2‐5 55 5.9 558 7.1 3 5.5 5.4 0.43 (0.14 – 1.38) 0.16 >5 26 2.8 252 3.2 2 7.7 7.9 0.63 (0.20 – 2.02) 0.44 COPD No 808 86.0 6786 86.2 79 9.8 11.6 Ref Yes 131 13.9 1079 13.7 2 1.5 1.9 0.15 (0.04 – 0.60) 0.008 Missing 1 0.1 7 0.1 0 0.0 0.0 Postsurgical ventilation No 468 49.8 3612 45.9 35 7.5 9.7 Ref Yes, abdominal surgery 338 36.0 3231 41.0 33 9.8 10.2 0.97 (0.60 – 1.56) 0.88 Yes, thoracical surgery 30 3.2 178 2.3 1 3.3 5.6 2.31 (0.32 – 16.9) 0.41 Yes, other surgery 104 11.1 851 10.8 12 11.5 14.1 0.88 (0.44 – 1.74) 0.71 Intubation site Oral 918 97.7 7641 97.1 79 8.6 10.3 Ref Nasal 6 0.6 53 0.7 0 0.0 0.0 0.00 (0.00 – inf) 0.99 Tracheostoma 14 1.5 167 2.1 1 7.1 6.0 0.37 (0.05 – 2.68) 0.32 Other 2 0.2 11 0.1 1 50.0 90.9 6.73 (0.92 – 49.1) 0.06 70 Chapter 4
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