Figure 4: Daily hazard ratios attributed to past values of the covariates assessed with a weighted cumulative effects approach in the multivariate Cox regression model: (A) ivSDD, (B) ivAB, (C) Jet nebulizer (compared to no inhalation therapy) and metered dose inhalers (MDI) (compared to no inhalation therapy). The curve shows the estimated risk attributed to exposures on each day prior to the last day of follow‐up (i.e., the event date or the censoring date) and the grey ribbon shows the 95% confidence interval. A value of one indicates no effect of the exposure at that time. At times where the grey ribbon includes one, the effect is considered to be statistically insignificant. 76 Chapter 4
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