41 Translocator protein expression in multiple sclerosis Table 1. Clinical details of multiple sclerosis and control cases Case Age Gender Genotype* Diagnosis Duration PM delay hrs:mins Cause of death Multiple sclerosis 1 69 F PPMS/SPMS 53 7:30 Respiratory failure 2 70 F PPMS/SPMS 40 6:55 Urine tract infection 3 50 M PPMS/SPMS 15 5:25 Pneumonia 4 66 F SPMS 11 6:00 Pneumonia 5 75 F PPMS/SPMS 24 5:00 Heart failure 6 49 M SPMS 25 8:00 Pneumonia 7 66 M SPMS 26 7:30 Ileus 8 64 F Low SPMS 31 10:10 Urinary tract infection 9 61 M High SPMS 18 9:15 Euthanasia 10 77 F PPMS 24 10:00 Euthanasia 11 67 F Mixed SPMS 25 9:15 Palliative sedation 12 45 M PPMS 10 7:45 Pulmonary embolism 13 59 F SPMS 24 4:45 Euthanasia 14 58 F SPMS 36 10:40 Euthanasia 15 44 M PPMS 21 10:15 End stage of MS 16 51 M SPMS 19 11:00 Unknown 17 57 F Low RRMS 26 8:40 Urosepsis 18 57 F High PPMS 29 11:00 Euthanasia 19 73 M Mixed RRMS 26 8:00 Urosepsis 20 76 F High SPMS 25 7:55 Euthanasia 21 56 M Mixed PPMS 14 9:50 Cachexia 22 74 M Mixed PPMS 15 10:15 Heart failure 23 60 F Mixed SPMS 7 10:40 Euthanasia 24 54 M Low PPMS 12 8:15 Euthanasia 25 75 M Mixed PPMS 46 10:10 Pneumonia 26 50 F Mixed SPMS 17 7:35 Euthanasia 27 53 M SPMS 24 10:00 Euthanasia 28 66 F PPMS 13 9:35 Euthanasia 29 56 M Mixed SPMS 14 10:10 Suicide 30 66 F SPMS 16 10:45 Pulmonary hypertension 31 81 F SPMS 31 4:35 Pneumonia 32 63 M SPMS 25 8:15 Pneumonia 33 75 F High SPMS Unknown 9:45 Subdural hematoma 34 61 F High Unknown Unknown 10:00 Euthanasia 35 50 M Low SPMS 21 10:50 Unknown 36 49 F Unknown Unknown 8:30 Unknown 37 50 F SPMS 18 09:05 Euthanasia 38 57 M PPMS 24 10:15 Sepsis 39 35 F SPMS 10 10:20 Euthanasia 40 54 F Unknown 27 09:25 Respiratory failure 41 67 M SPMS 38 11:00 Sudden death 42 54 M SPMS 29 06:40 Euthanasia Biopsy 1 51 M Demyelinating disease, suspected MS 2 Unknown Demyelinating disease, suspected MS 3 27 M Demyelinating disease, suspected MS 4 31 F Demyelinating disease, suspected MS Control 1 61 F control N/A 6:50 Euthanasia 2 73 F control N/A 4:00 Lung fibrosis 3 67 M control N/A 4:30 Cardiac shock 4 81 M control N/A 5:30 Prostate carcinoma 5 67 M control N/A 18:35 Myocardial infarction 6 84 F control N/A 4:45 Respiratory failure 7 91 F control N/A 7:45 Decompensatio cordis 8 56 M Mixed control N/A 14:00 Heart failure 9 92 F control N/A 7:00 Acute death 10 62 M Mixed control N/A 7:20 Unknown 11 49 M Mixed control N/A 6:15 Euthanasia 12 51 M control N/A 7:30 Euthanasia *cases selected for autoradiography, F = female, M = male, MS = multiple sclerosis, N/A = not applicable, PM = post mortem, PP = primary progressive, RR = relapsing remitting, SP = secondary progressive.
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