Erik Nutma

Chapter 1 General introduction | Inflammation in CNS neurodegenerative diseases 9
Chapter 2 A quantitative neuropathological assessment of translocator protein expression in multiple sclerosis 37
Chapter 3 Activated microglia do not increase 18 kDa translocator protein expression in the multiple sclerosis brain 61
Chapter 4 Translocator protein is a marker of activated microglia in rodent models but not human neurodegenerative diseases 77
Chapter 5 Cellular sources of TSPO expression in healthy and diseased brain 113
Chapter 6 Synaptic Loss in Multiple Sclerosis Spinal Cord 141
Chapter 7 Astrocyte and oligodendrocyte crosstalk in the central nervous system 155
Chapter 8 White matter microglia heterogeneity in the CNS 177
Chapter 9 General discussion | Imaging immunological processes from blood to brain in amyotrophic lateral sclerosis 201
APPENDICES 215
Summary 216
Nederlandse samenvatting 220
List of publications 224
Dankwoord 226
About the author 229

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