141 Body composition measurement methods in preterm infants 7 Results Quality assessment Results include preterm as well as term infants Weight and length accounted for >97% of the variance of fat free mass (g) in AGA and SGA infants and 46% of the variance in LGA infants. Midarm to head circumference ratio and midarm/thigh muscle areas accounted for respectively 17% and 6% of the variance in fat free mass (g). Chest, abdomen, midarm and midthigh circumference did not explain any additional part of the variance in fat (free) mass (g) after including gender, race, gestation, weight and length in the predictive equation. Level of evidence 4 Strengths & limitations Assessment of agreement with reference method – Assessment of intra- and interobserver variability + Repeated measurements + Coefficients of variance assessed – Sensitivity analysis – Bootstrapping analysis – Cross validation group – External validation – Large study population – Exclusively preterm infants – Mid-arm circumference was a covariate for fat mass percentage and accounted for 60.4% of the variance. Level of evidence 2 Strengths & limitations Assessment of agreement with reference method – Assessment of intra- and interobserver variability – Repeated measurements + Coefficients of variance assessed – Sensitivity analysis – Bootstrapping analysis – Cross validation group – External validation – Large study population – Exclusively preterm infants – Mid-arm circumference predicted 41% of the variance in midarm circumference measured by MRI Arm fat and muscle area predicted respectively 40% and 7 % of the variance in the area measured by MRI Mid-arm circumference predicted 4.8% of the variance in arm fat are (mm2) measured by MRI Level of evidence 2 Strengths & limitations Assessment of agreement with reference method – Assessment of intra- and interobserver variability + Repeated measurements + Coefficients of variance assessed + Sensitivity analysis – Bootstrapping analysis – Cross validation group – External validation – Large study population – Exclusively preterm infants + 51% of the variance in fat mass percentage could be explained by weight-length indices before 50 weeks PMA and 16% after 50 weeks PMA The best fit regression model most closely matched BMI Level of evidence 4 Strengths & limitations Assessment of agreement with reference method – Assessment of intra- and interobserver variability – Repeated measurements – Coefficients of variance assessed – Sensitivity analysis – Bootstrapping analysis – Cross validation group – External validation – Large study population + Exclusively preterm infants +
RkJQdWJsaXNoZXIy MTk4NDMw